Over 646 million BLE-enabled devices are used in hospitals, clinics, and medical offices — and BLE’s commoditization is redefining RTLS hardware entirely. This white paper explains how the combination of standard off-the-shelf BLE 5.1 hardware, machine learning, and computational horsepower is making room-level and sub-room accuracy affordable and accessible across healthcare. Covers five core RTLS use cases: asset tracking, wayfinding and patient experience, hand hygiene compliance, staff locating and duress, and patient safety and workflow.